Faculty Detail

Dr Sarika Saxena

Associate Professor

Amity Institute of Biotechnology

Qualifications
Graduation : B.Sc.(Chemistry, Zoology)-1995,Delhi University

Post Graduation : M.Sc.(Biochemistry)-1997,Jamia Hamdard, New Delhi

Doctorate : Ph.D.(Biophysics)-2004,University of Delhi

Post Doctorate : PDF(Biophysics and Nanobiotechnology)-2008,Frontier Institute of Biomolecular Engineering and Research (FIBER), Konan University, Japan

Post Doctorate : PDF-2010,FIBER, Konan University, Japan
Experience
01 Jun 2006 - Present
Associate Professor,
Amity Institute of Biotechnology

16 Sep 2010 - 16 Jul 2012
Assistant Prof.,
Amity University Uttar Pradesh,
Amity Institute of Biotechnology, Amity University Uttar Pradesh, Noida, U.P.

01 Jul 2008 - 01 Jul 2008
PDF,
Frontier Institute of Biomoleclar Engineering and Research,
FIBER, Konan University, Japan

01 Jun 2006 - 01 Jun 2006
Lecturer,
Amity University Uttar Pradesh,
Amity Institute of Biotechnology, Amity Unersity Uttar Pradesh, Noida, U.P.

01 Jun 2005 - 01 May 2006
Guest Lecturer,
Delhi Technological University,
Delhi Technological University, Bawana

01 Jun 2004 - 01 May 2005
Project Associate,
Institute of Genomics and Integrative Biology,
Institute of Genomics and Integrative Biology, Mall Road, Delhi-110007

01 Jun 2003 - 01 Apr 2004
Project Associate,
Institute of Genomics and Integrative Biology, CSIR,
Institute of Genomics and Integrative Biology, CSIR, Mall Road, Delhi-110007
Current Courses Taught
Biophysics and Structural Biology
Publications
Structural and Functional Characterization of RecG Helicase Enzyme under Dilute and Molecular Crowding Conditions. ,
Journal of Nucleic Acid

Structural Diversity and Specific Recognition of four stranded G-quadruplex DNA ,
Current Molecular Medicine

Conformational Flexibility influences degree of hydration of nucleic acids. ,
Jopurnal of Physical Chemistry B

Thermodynamic Stability of Hoogsteen and Watson-Crick base pairs in the presence of histone H3 mimicking peptide under molecular crowding condition. ,
Chem. Comm. (camb)

Sole and stable RNA duplexes of G-rich sequences located in the 5'-untranslated region of protooncogenes. ,
Biochemistry

Monomorphic RNA G-quadruplex and polymorphic DNA G-quadruplex structures responding to cellular environmental factors. ,
Biochemistry

Structural polymorphism at LCR and its role in beta-globin gene regulation. ,
Biochemie

Structural polymorphism exhibited by a homopurine.homopyrimidine sequence found at the right end of human c-jun protooncogene ,
Archeives of Biochemistry and Biophysics

Possibility of an Antiparallel (Tetramer) Quadruplex exhibited by the double repeat of the Human Telomere. ,
Biochemistry

HEPNet: A Knowledge Base Model of Human Energy Pool Network for Predicting the Energy Availability Status of an Individual ,
PLOS

HEPNet: A Knowledge Base Model of Human Energy Pool Network for Predicting the Energy Availability Status of an Individual ,
PLOS

A Computational Model of Mitochondrial Beta- Oxidation Highlighting the Implications on Uremia Disease in Human. ,
International Journal of Soft Computing and Engineering.

A Computational Biology approach to decipher significant intricacies of Dihydrolipoamide Dehydrogenase deficiency in Human. ,
International Journal of Soft Computing and Engineering

HEPNet: A Knowledge Base Model of Human Energy Pool Network for Predicting the Energy Availability Status of an Individual. ,
PLoS ONE

HEPNet: A Knowledge Base Model of Human Energy Pool Network for Predicting the Energy Availability Status of an Individual. ,
PLoS ONE
Projects
To study the effect of natural molecular crowding agents on the structure and stability of nucleic a(Not applicable)
Nucleic acid structure and its stability entirely depend on the molecular environment, referred as molecular crowding. It has been reported so far that concentration of biomolecules reaches 400 gl-1 inside the cell and referred as molecular crowding. Molecular crowding certainly dffers from individual to individual in some respect for ex. individual suffering from diabetes or suffering from kidney failure because of the involvement and alterations of different metabolic pathways. So my questionby (DST)
Affiliations
Chemical Society of Japan Since 01 Dec 2009
Conferences attended
Monomorphic structure of G-rich RNA sequences and polymorphic structure of G-rich DNA sequences resp
Organized By :International Chemical Congress of Pacific Basin Societies, Hawaii.

Sole and stable RNA duplex of G-rich sequences located in 5'-untranslated region of protooncogenes.
Organized By :Japan Chemical Society

Highly polymorphic unstable to highly monomorphic stable: Structural mystery of GC rich DNA and RNA
Organized By :FIBER, Konan University, Japan

Regulation of Gene Expression using Antigene Strategy
Organized By :International Symposium on Trends in Medicinal Chemistry and Biocatalysis North campus Delhi University

Duplex and Triplex DNA: Stabilization Aspects
Organized By :International Symposium on Trends in Medicinal Chemistry and Biocatalysis

Interaction of Proflavine and Acridine Orange with Polymorphic DNA Sequences
Organized By :Department of Chemistry, Guru Nanak Dev University Amritsar

Alpha-helix and Beta-strand: preactive and active structure of RecG under dilute and molecular crowd
Organized By :Jamia-Milia-Islamia

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