Dr Reshma Rani

Asst. Professor (Grade - II)

Amity Institute of Biotechnology
 
  • Qualifications

    Graduation : -2000,M. J. P Rohilkhand University bareilly

    Post Graduation : -2003,IIT Roorkee

    Doctorate : -2010,IIT Roorkee

  • Experience

    05 Dec 2016 - Present
    Asst. Professor (Grade - II),
    Amity Institute of Biotechnology



  • Current Courses Taught

    Bio-organic and Medicinal Chemistry

    Essentials of Material Science for Biologists

    Good lab practices and Instrumentation

    Instrumentation in Biomedicine

    Principles of Physical Chemistry

  • Publications

    Recent Update on Human Lactate Dehydrogenase Enzyme 5 (hLDH5) Inhibitors: A Promising Approach for Cancer Chemotherapy ,
    American Chemical Society

    Microwave Energy: A Potential and Efficient Source of Energy in Pharmaceutical Chemistry

    Bioactive heterocycles containing endocyclic N-hydroxy groups

    “LDH-A/p53 regulate cancer cell NAD(H) enabling therapeutic access to cancer cell killing via LDH-A by both p53-dependent and p53-independent pathways ,
    Nature publishing group

    Synergistic interaction of novel lactate dehydrogenase inhibitors with gemcitabine against pancreatic cancer cells in hypoxia ,
    Nature publishing group

    Small-molecule inhibitors of human lactate dehydrogenase 5 (hLDH5) ,
    Future Medicinal Chemistry

    Synthesis of bis-acridine derivatives exhibiting anticancer and anti-inflammatory activity ,
    Journal of Heterocyclic Chemistry

    Synthesis, anti-inflammatory, and cytotoxicity evaluation of 9,10-dihydroanthracene-9,10-a,ß-succinimide and bis-succinimide derivatives ,
    Medicinal Chemistry Research

    An expeditious, highly efficient, catalyst and solvent-free synthesis of 9,10-dihydro-anthracene-9,10-a,b-succini-imide derivatives” ,
    Green Chemistry Letters and Reviews

    Microwave-assisted conversion of aromatic heterocyclic nitriles to various heterocyclic molecules ,
    Green Chemistry Letters and Reviews

    Synthesis, anti-inflammatory and anticancer activity evaluation of some mono- and bis-Schiff's bases ,
    Medicinal Chemistry Research,

    Synthesis, Anti-inflammatory & Anticancer Activity Evaluation of Some Heterocyclic Amidine and Bis-amidine Derivatives ,
    Journal of Heterocyclic Chemistry

    Microwave-mediated one step synthesis of tri and tetracyclic heterocyclic molecules ,
    Green Chemistry Letters and Reviews

    Solvent free synthesis, anti-inflammatory & anticancer activity evaluation of tricyclic and tetracyclic benzimidazole derivatives ,
    Bioorganic & Medicinal Chemistry Letters

    Conventional and microwave assisted synthesis of small molecule based biologically active heterocyclic amidine derivatives ,
    European Journal of Medicinal Chemistry

    Synthesis, anti- inflammatory and anticancer activity evaluation of some novel acridine derivatives ,
    European Journal of Medicinal Chemistry

    Synthesis, anticancer, and anti- inflammatory activity evaluation of methanesulfonamide and amidine derivatives of 3,4-diaryl-2-imino-4- thiazolines. ,
    Molecular Diversity

    Microwave-assisted synthesis of N-substituted cyclic imides and their evaluation for anticancer and anti-inflammatory activities. ,
    Bioorganic & Medicinal Chemistry Letters

    Synthesis, Antiinflammatory and Analgesic Activity Evaluation of Some Pyrimidine Derivatives ,
    ChemInform

    Synthesis of some heterocyclic imides and azomethine derivatives under solvent free condition and their anti-inflammatory activity evaluation. ,
    Journal of Heterocyclic Chemistry

    A convenient, solvent free and high yielding synthesis of bicyclo- heterocyclic compounds ,
    Letters in Organic Chemistry

    Heterocyclic compounds as anti- inflammatory agents ,
    Current Bioactive Compounds

    Bioactive Heterocycles Containing Endocyclic N- Hydroxy Groups ,
    ChemInform

    When will small molecules Lactate dehydrogenase inhibitiors realize their potential in the cancer clinic ,
    Future Medicinal Chemistry

    Fluorescent Carbon Nanoparticles in Medicine for Cancer Therapy: An Update ,
    American Chemical Society

    Regulation/inhibition of human Lactate dehydrogenase A: An innovative and potential Approach for Anticancer Drugs Development ,
    Bentahm Science Publisher

    When will small molecules Lactate dehydrogenase inhibitiors realize their potential in the cancer clinic ,
    Future Medicinal Chemistry

    Fluorescent Carbon Nanoparticles in Medicine for Cancer Therapy: An Update ,
    American Chemical Society

    Regulation/inhibition of human Lactate dehydrogenase A: An innovative and potential Approach for Anticancer Drugs Development ,
    Bentahm Science Publisher

    Selective inhibitors of human lactate dehydrogenase A to fight against metabolic cancer: a patent landscape ,
    Future Science Group

    Tumor Metabolism: Focused on Tumor Glycolysis, Progress and Prospects in Cancer Therapy ,
    John Wiley and Sons Ltd

    In Silico Approach in Drug Design and Drug Discovery: An Update. ,
    Springer

    Fourier transform infrared spectroscopy: Data interpretation and applications in structure elucidation and analysis of small molecules and nanostructures ,
    Elsevier

    Small molecules inhibitors of the Plasmodium Falciparum LDH enzyme and their therapeutic applications ,
    nova science

    LACTATE DEHYDROGENASE ENZYME: AN OLD ENZYME BUT NEW VIABLE TARGET OFFERS NEW HOPE IN CANCER THERAPEUTICS ,
    nova science

  • Projects

    Design and Synthesis of Selective Inhibitors of human Lactate Dehydrogenase 5(hLDH5): Targeting the (NA)
    NAby (SERB)

  • Activities

    1. “Marie Curie Postdoctoral Fellowship” (2012-2014) European Community - 7th Research Framework Programme: FP7-PEOPLE-2011-IIF, Proj. n. 299026 "LACTABLOCK" (2012-2014).

    Postdoctoral fellowship (2011) The Institute of Scientific and Industrial Research (ISIR) Osaka University Japan.

    First Prize for presenting research paper in National Conference cum Technical workshop (Cognizence-2010), on 26rd -28th March held at Indian Institute of Technology Roorkee, India

    Third Prize for presenting research paper in National Conference cum Technical workshop (Cognizence-2007), on 23rd -25th March held at Indian Institute of Technology Roorkee, India.

    Senior research fellow Award 2007-2010 (CSIR - National level) conducted by Government of India.

    Junior research fellow Award 2005-2007 (CSIR - National level) conducted by Government of India.

    Qualified UGC-CSIR JRF (2004)

    UGE-NET-LS (2003).

    Qualified Entrance exam for the admission in M.Sc. (Chemi

    Early Career Research Award, SERB, DST-India- 2017-2020

    Indian Brand Ammasdor Bentham Science 2020

    Indian Society of Analytical Science (Life time member) member Id LM-2019/61

    Life time member Marie Curie Alumni Indian Chapter (Indian)

    :Life time member Marie Curie Alumni Italian Chapter (Italian)

    Review board Members Frontiers in Chemistry

  • Conferences attended

    Achievements of Women in Science and Technology: Current Scenario and Future Prospects
    Organized By :Punjab University Chandigarh

    Molecular and clinical Target: PI3K/mTOR inhibitors
    Organized By :National Cancer Institute (CRO), Aviano

    Novel Synthetic Procedure in Medicinal Chemistry and HIV Research” topic: Small molecules inhibitors
    Organized By :Maharaja Agarsen University Baddi, Himachal Pradesh

    European workshop in Drug synthesis “Novel Synthetic Procedure in Medicinal Chemistry and HIV Resear
    Organized By :, Certosa di pontignano, Siena, Italy

    Tuscany Europe 2020 Marie Curie Action: On The Last Lap to Horizon 2020” “Discovery of small molecul
    Organized By :European Commission in Italy

    7th EFMC Short Course on Medicinal Chemistry: “Principles of Molecular Recognition
    Organized By :University of lieden

    National Conference cum Technical Workshop (Cognizance- 2010)
    Organized By :Indian Institute of Technology Roorkee

    National Conference cum Technical Workshop (Cognizance- 2010)
    Organized By :Indian Institute of Technology Roorkee

    Contemporary Facets in Organic Synthesis (CFOS2017)
    Organized By :Indian Institute of Technology Roorkee