Dr Pratima Chaudhuri

Professor

Amity Institute of Biotechnology
 
  • Qualifications

    Graduation : B.Sc(Chemistry)-1985,Calcutta University

    Post Graduation : M.Sc(Inorganic Chemistry)-1988,Calcutta University

    Doctorate : Ph.D.(Chemistry)-1996,Calcutta University

  • Experience

    02 Aug 2004 - Present
    Professor,
    Amity Institute of Biotechnology

    01 Apr 2008 - 30 Jun 2008
    Visiting Professor,
    National Institute of Natural Sciences, Okazaki, Japan,


    10 Jun 2007 - 11 Jul 2007
    visiting Professor,
    Chiba Institute of Technology, Japan,
    Chiba, Tsudanuma, JAPAN

    01 Mar 2004 - 28 Jul 2004
    RESEARCH ASSOCIATE,
    DBT FUNDED PROJECT AT IIT, DELHI,


    01 Apr 2003 - 28 Mar 2004
    Divisional Manager,
    Genotech,USA,


    01 Nov 2001 - 28 Aug 2002
    POSTSOCTORAL RESEARCH ASSOCIATE,
    DEPARTMENT OF MEDICINAL CHEMESTRY, COLLEGE OF PHARMACY, UNIVERSITY OF UTAH, USA,


    01 Jan 1999 - 28 Aug 2001
    POSTDOCTORAL RESEARCH ASSOCIATE,
    DEPT. OF GENETICE, YALE UNIVERSITY SCHOOL OF MEDICINE, NEW HAVAN, CONNECTICUT, USA,


    01 Aug 1997 - 28 Sep 1998
    POSTDOCTORAL FELLOW,
    DEPARTMENT OF INDUSTRIAL CHEMESTRY, CHIBA INSTITUTE OF TECH., CHIBA, JAPAN,


    09 Sep 1989 - 17 Jul 1995
    Ph.D student,
    DEPARTMENT OF CHEMESTRY, AND UNIVERSITY COLLEGE OF SCIENCE & TECH., CALCUTTA,


  • Current Courses Taught

    Animal Biotechnology

    Chemical Biology

    Research Techniques in Biosciences and Biotechnology

  • Publications

    Structural characterization of the mechanosensitive channel candidate MCA2 from Arabidopsis thaliana ,
    PLOS ONE

    Induction of apoptosis using gene therapy in the treatment of cancer ,
    Journal of oncology and hematology

    1. “AA-dUTP-Cy3 a novel fluorescent labeling agent for nucleotides ,
    Journal of Biochemistry & Pharmacology:

    1.“AA-dUTP-Cy3 a novel fluorescent labeling agent for nucleotides ,
    Journal of Biochemistry & Pharmacology:

    Biochemical and biophysical studies of the dimerization process of HIV-RNA genome ,
    Research and reviews:A Journal of medicine

    Structure-activity corelationship and folding of recombinant Escherichia coli dihydrofolate reductase (DHFR) enzyme through biochemical and biophysical approaches ,
    Journal of biophysical chemistry

    A global survey of haplotype frequencies and linkage disequilibrium at the RET locus ,
    European Journal of Human genetics

    Structural requirement for two step dimerization of human Immuno Deficiency Virus type-1 genome ,
    RNA

    An NMR and mutational analysis of an RNA pseudoknot of E.coli tmRNA involved in translation ,
    Nucleic Acids Res

    Dynamics of complex formation in M(II(-Nitrilo-Triacetate-L systems (M-cobalt (II), Nickel(II);L-SCN,Bipy,Phen) ,
    Polyhedron

    Comparative physicochemical characterisation of recombinant DHFR from E.coli, Zebrafish and human origin ,
    Asian congress of biotechnology

    Revisiting the unfolding pathway of Dihydrofolate reductase as an anti-cancer drug target ,
    Frontiers in Cancer research: Prevention to therapeutics

    Monitoring folding and unfolding processes of recombinant DHFR from different species towards designing of anticancer drugs ,
    IISC-Protein folding and diseases

    Characterization of recombinant DHFR towards designing of an anticancer drug ,
    World congress of Biotechnology

    Characterization of recombinant DHFR towards designing of an anti cancer drug ,
    Perspectives of cell signalling and molecular medicine

    NMR study on the conformational conversion of the dimerization initiation site of the HIV-1 genomic RNA ,
    ISNAC, Tokyo, Japan

    Physico-chemical and functional characterization of E.coli DHFR, an enzyme targeted for anti-cancer drug design ,
    Current trends in advanced Biomedical technology

    Conformational alteration of retro viral RNA genome during dimerisation process ,
    Joint Indo Korean symposium on Biochemical Enigineering and biotechnology

    Comparison of bioreactor performances for urokinase production from human kidney cell line HT-1080 ,
    Chemcon

    Linkage disequilibrium across 150Kb region around RET gene on chromosome 10 ,
    American journal og human genetics

    Two dimeric forms of the isolated dimerization initiation site of HIV-1 genome ,
    ICMRBS,Japan

    A monomeric form of the isolated dimerization initiation site of HIV-1 genome ,
    ICMRBS,Japan

    comparison of Physico-chemical aspects between E.Coli and human Dihydrofolate Reductase: an equilibrium unfolding study ,
    Springer

    1. “Comparison of physico-chemical aspects between E.coli and Human DihydrofolatReductase:An equilibrium unfolding study” ,
    Springer

    1. “Comparison of physico-chemical aspects between E.coli and Human DihydrofolatReductase:An equilibrium unfolding study” ,
    Springer

    2. “Effect of various osmolytes on expression and functionality of Zebrafish Dihydrofolate reductase: an in vivo study”

    Effect of various osmolytes on expression and functionality of Zebrafish Dihydrofolate reductase: an in vivo study ,
    Journal of proteins and proteomics

    Effect of various osmolytes on expression and functionality of Zebrafish Dihydrofolate reductase: an in vivo study ,
    Journal of proteins and proteomics

    “Comparison of physico-chemical aspects between E.coli and Human DihydrofolatReductase: An equilibrium unfolding study” ,
    Biophysics

    “Comparison of physico-chemical aspects between E.coli and Human DihydrofolatReductase: An equilibrium unfolding study” ,
    Biophysics

    “Investigation of folding unfolding process of a new variant ofdihydrofolate reductase protein from Zebrafish ,
    International journal of biological macromolecules

    “Investigation of folding unfolding process of a new variant ofdihydrofolate reductase protein from Zebrafish ,
    International journal of biological macromolecules

    Dihydrofolate reductase as a drug target in health care ,
    Journal of proteins and proteomics

    Osmolyte induced enhancement of expression and solubility ofhuman dihydrofolate reductase: An in vivo study ,
    ELSEVEIR

    Kinetics and thermodynamics of the thermal inactivation and chaperone assisted folding of zebrafish dihydrofolate reductase ,
    Elsevier

    Quantification of differential efficacy of chemical chaperones in ameliorating solubilization and folding of zebrafish dihydrofolate reductase ,
    Elsevier

    Stability and refolding of Dihydrofolate reductase enhances with nano-conjugation ,
    Elsevier

    A versatile tool in controlling aggregation and Ag nanoparticles assisted in vitro folding of thermally denatured zDHFR ,
    Elsevier

  • Projects

    Developing assisted foldinfg processes in recombinant proteins for production enhancement(no other institution)
    enhancement of proteins by assited folding processes.by (CSIR)

    “Nanoparticle mediated initiatives for enhancement of recombinant Dihydrofolate Reductase protein pr(IIT delhi)
    Nanoparticle mediated initiatives for enhancement of recombinant Dihydrofolate Reductase protein preparation in Escherichia coli cytosol and in vitro: A Bio- Nanotechnologyby (DBT)

  • Patents

    Process for the synthesis of AA-dUTP-Cy3/Cy5- a novel fluorescent labeling agent ,Delhi,India - Complete ( 1529/DEL/2009 )

    Preparation and characterization of the recombinant membrane protein (MCA2) in the Sf9 insect cell line ,Delhi,India - Complete ( 2592/DEL/2011 )

    “Efficient protein folding process to improve the functional yield of recombinant zDHFR protein” ,Delhi,India - Provisional ( 2170/DEL/2015 )

  • Conferences attended

    National symposium on Biophysics and Golden Jubilee Meeting of Indian Biophysical Society
    Organized By :Jamia Millie islamia

    National symposium on Biophysics and Golden Jubilee Meeting of Indian Biophysical Society
    Organized By :Jamia Millie islamia

    Workshop On Molecular Modeling and Docking Studies
    Organized By :Amity university

    Stem Cell, Cancer and Drug Discovery
    Organized By :Amity University

    PSIAOAPO 2016
    Organized By :Protein society of india

    Innopharm 2
    Organized By :Innovare academic sciences

    International Conference on Translational Research: Application in Human Health and Agriculture
    Organized By :INDIAN SOCIETY OF TRANSLATIONAL RESEARCH, INDIA

    International Conference on Translational Research: Application in Human Health and Agriculture
    Organized By :INDIAN SOCIETY OF TRANSLATIONAL RESEARCH, INDIA

    International Conference on Translational Research: Application in Human Health and Agriculture
    Organized By :INDIAN SOCIETY OF TRANSLATIONAL RESEARCH, INDIA

    International Conference on Translational Research: Application in Human Health and Agriculture
    Organized By :INDIAN SOCIETY OF TRANSLATIONAL RESEARCH, INDIA

    “Protein Structure and Dynamics in Health and Agriculture”
    Organized By :Protein Society of India

    Protein Folding and Dynamics
    Organized By :Gordon Research Conference